The commercial and cultural center for the Ruhr region on the Rhine River, Duseldorff is also the site of the Felderhof Cave where Neanderthal man was found in 1856.

Located on the north coast of Morocco near the Strait of Gibraltar, Tangier is a cultural capital replete with historic sites, colorful architecture, and splendid beaches. An essential stop is the Ancien Medina, a walled collection of winding streets and alleys filled with cafes and shops leading to the Kasbah, a former palace and mosque that also houses a museum.

Formally called Ocean Cay MSC Marine Reserve, Ocean Cay is a private island only accessible to MSC Cruises guests. Activities include beachside lounging, snorkeling, paddle boarding, lighthouse climbing, dining, shopping and more.

Khiva, located in western Uzbekistan’s Khorezm region, is one of Central Asia’s most evocative Silk Road cities.

Set on the Adriatic Sea, Zadar, Croatia, is a major Dalmatia historical center and a tourism magnet. Walk ancient streets, see Roman ruins and enjoy white-sand beaches.