Cusco once served as the heart of the Inca Empire, and that legacy still shapes every corner of the city even as it serves as a gateway to Machu Picchu. Outside the historic center, the ruins of Sacsayhuamán overlook the city from a nearby hilltop. This ceremonial complex is best known for its massive zigzag stone walls, some weighing over 100 tons. During the Inti Raymi festival in June, thousands gather here to reenact ancient Andean rituals.

Granada, Nicaragua, founded in 1524, is one of the oldest European-established cities on the mainland of the Americas where visitors can explore cobblestone streets lined with brightly painted facades. The mustard-yellow Granada Cathedral dominates the central park and provides an easy reference point for those navigating the city on foot or by traditional horse-drawn carriage.

Ensenada is an enchanting port city on the coast of Baja California, Mexico. Stroll along the harbor on the Malecón Promenade for spectacular panoramic views of the Pacific Ocean, or hit the town for a taste of Ensenada's thrilling night life and delectable local eats.

Agrigento, located on the southern coast of Sicily, is a city steeped in history and renowned for its ancient Greek ruins. The crown jewel of Agrigento is the Valley of the Temples, a UNESCO World Heritage Site and one of the most spectacular archaeological sites in the Mediterranean. Visitors can marvel at the remarkably preserved Temple of Concordia, which dates back to the 5th century BC and is considered one of the best-preserved Greek temples in the world.

Valparaíso, Chile, is a city that beckons travelers with its vibrant street art, steep hillsides, and bohemian spirit. Known as the "Jewel of the Pacific," Valparaíso's historical importance as a major port during the 19th century has left an indelible mark on its architecture and culture.